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Measures and Testing for IIS Validation - Query and Response

Final IIS Validation measures and tests related to query and response developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Assessing the Immunization Information System and Electronic Health Record Interface Accuracy for COVID-19 Vaccinations

Immunizations in the United States are given in many different settings including pharmacies, doctors’ offices, and health departments. After a vaccine is administered, the information is uploaded to an Immunization Information System (IIS), usually run by t...

Monkeypox Preferred Select Codes

Monkeypox Preferred Select Codes

Issued on November 3, 2022 by AIRA

This document addresses select codes for monkeypox that are not clearly articulated in interoperability documents. These codes were approved by AIRA’s Standards and Interoperability Steering Committee (SISC, a diverse committee with broad representation from...

Preparing for COVID-19 Vaccination: A Call to Action for Clinicians on Immunization Information Systems

Annals of Internal Medicine article regarding a call to action for clinicians on IIS in preparation for COVID-19 vaccination

IIS Operations Tools

IIS Operations Tools

Issued on September 22, 2020 by PHII

The IIS Operations Tools page empowers IIS staff to navigate the various processes involved in managing and maintaining the day-to-day operations of a well functioning IIS. This set of tools was developed by the Public Health Informatics Institute with input f...

Advanced HL7 for IIS

Advanced HL7 for IIS

Issued on January 26, 2018 by PHII

This course builds on HL7 Basics to dive deeper into how HL7 works. Learners will explore conformance, constraints, and message profiles. We'll also cover how the Implementation Guide constrains the HL7 standard, how local specifications are set up, and how co...

Immunization Information System Functional Standards, v4.0

This document sets forth the IIS Functional Standards and Operational Guidance Statement (OGS) to guide the direction and progress of IISs over the next five years.

How Using Bi-Directional State Registry Data Changes Immunization Rates

Issued on July 19, 2017 by Scientific Technologies Corporation

Article | This study found a 40% increase in additional vaccinations given at the time of flu shots when pharmacists had access to IIS data

Toolkit for Preparing to Access CMS 90-10 Funding for Public Health

Toolkit | This planning toolkit provides guidance on preparing to work with Medicaid on securing federal matching funds. Those funds can be used to support IIS readiness for Meaningful Use and Health Information Exchange. The toolkit includes tip sheets and wo...

Article | Lessons learned from three pharmacy case studies about the potential benefit of IIS to both the pharmacy and public health

This addendum consolidates the Implementation Guide information that clarifies the conformance requirements. This supplement does not specify additional requirements; it just clarifies existing ones. Value set requirements, general clarifications, and Immuniza...

Health Level Seven (HL7) is a nationally recognized standard for electronic data exchange between systems housing health care data. The HL7 standard is a key factor that supports this two-way exchange of information because it defines a syntax or grammar for f...

The purpose of this document is to define and provide supporting references to the Immunization Information System (IIS) Functional Standards for 2013-2018