Resource Repository

Article | This study evaluates the impact of using IIS data to identify unmet vaccination needs in adults seeking the influenza vaccine. The study found a 41.4% increase in the number of vaccines administered, and significant improvements in routinely recomme...

National Meeting Presentation | Project IMPACT Immunizations: IMProving America’s Communities Together

Annals of Family Medicine article regarding the strategies used for maintaining routine vaccination rates.

Annals of Internal Medicine article regarding a call to action for clinicians on IIS in preparation for COVID-19 vaccination

National Meeting Presentation | DAR DQ Report Assessment and Distribution Through the AZ Report Suite (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete without the ac...

National Meeting Presentation | Characterizing Clinical Decision Support for HPV Vaccination in Immunization Information Systems (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and ar...

Data Use Agreement with APHL (Association of Public Health Laboratories) for participation in both IZ Gateway Connect and IZ Gateway Share (updated August 3, 2020)

National Meeting Presentation | ASTHO IIS Interstate Data Exchange Meeting

National Meeting Presentation | The Public Health Community Platform: A Community Resource for Shared Solutions

National Meeting Presentation | Registry View: How EHRs can contribute to IIS Success

National Meeting Presentation | Using Automated Solutions to Effectively Manage Stage 2 Meaningful Use Challenges

National Meeting Presentation | Meeting Stage 2 Meaningful Use Challenges and Automated Solutions

National Meeting Presentation | Automating Electronic Health Record (EHR) Integration

National Meeting Presentation | IZ Gateway Future Vision & Listening Session (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2021 National Meeting and are incomplete without the accompanying oral commenta...

National Meeting Presentation | Arizona IIS Migrated to Cloud

National Meeting Presentation | Patient Deduplication - Going Beyond the Automated Function

National Meeting Presentation | Better Immunization Data Initiative

This article summarizes a systematic literature review of potential barriers to public health data sharing

National Meeting Presentation | Expanded Program on Immunization (EPI) in Bogotá: Ensuring Data Quality

National Meeting Presentation | Using Immunization-related Clinical Comments for Advanced Immunization Forecasting

National Meeting Presentation | Brazil's Nominal Information System: Innovating Vaccination Records, Integrating Databases and Providing Outputs for Analysis

National Meeting Presentation | Information System to Evaluate Vaccine Loss

National Meeting Presentation | Using AI in IIS Projects to Develop and Reference Guidance Documentation (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the...

National Meeting Presentation | Using Terms and Rules in Public Health: Are We Speaking the Same Language?

National Meeting Presentation | Innovation in Modernizing IIS HL7 Data and Knowledge (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete without the accompanying oral c...

National Meeting Presentation | Managing Business Rules & Decisions: Making Knowledge Explicit

National Meeting Presentation | Capturing and Implementing Business Rules and Decisions — The Intellectual Capital of Your Organization

National Meeting Presentation | Case Study in the Management of Common IIS Rules, Vocabulary, and Operational Decisions

National Meeting Presentation | CAIR2 Patient Matching: Solving the 25 Million Piece Puzzle

National Meeting Presentation | CAIR Before and After: The Evolution of Implementing a New State IIS

National Meeting Presentation | Data Migration Lessons Learned, Data Quality Opportunities for Data at Rest

National Meeting Presentation | California’s Immunization Gateway Portal: Fulfilling Business Needs by Simplifying Interoperability

National Meeting Presentation | Alternative Race/Ethnicity Categorization of COVID-19 Vaccine Recipients (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2023 National Meeting and are incomplete without the...

National Meeting Presentation | Designing Self-Service Analytics and Data Viz to Support Outbreak Response (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2023 National Meeting and are incomplete without t...

National Meeting Presentation | COVID-19 Co-vaccination of Pediatrics in CA: Successes & Missed Opportunities (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2023 National Meeting and are incomplete withou...

National Meeting Presentation | A Tale of Two Views: Organization of California's COVID-19 Vaccination Data (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2022 National Meeting and are incomplete without ...

National Meeting Presentation | Mind the Gap: Analyzing the Impact of COVID-19 on Routine Immunizations (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2022 National Meeting and are incomplete without the ...

National Meeting Presentation | Instant Answers! How GenAI Can Answer Your Immunization Questions (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete without the accomp...

National Meeting Presentation | Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete wit...

National Meeting Presentation | CAIR Quick Entry: Turbocharging Provider Efficiency in Vaccination Data Uploads (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete with...

National Meeting Presentation | Unveiling California’s Health Data Revolution: The Master Patient Index Solution (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete w...

National Meeting Presentation | Mastering Data: AI-Enabled Data Management and Person Identity (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete without the accompany...

National Meeting Presentation | Plenary CDC Update (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2021 National Meeting and are incomplete without the accompanying oral commentary and discussion.)

The IISAR is an annual survey that assesses immunization program performance in developing, maintaining, and enhancing Immunization Information Systems for a given calendar year. It is a reporting requirement for the 64 immunization programs that receive fundi...

These links and documents have been compiled to assist the immunization community in their COVID-19 planning and preparation. This list may not be complete and will likely be updated frequently as new information is released. We also encourage you to check CDC...

National Meeting Presentation | CDC Immunization Quality Improvement Program: Leveraging IIS Functionality

National Meeting Presentation | New Strategies for Using IIS to Monitor and Improve Vaccination Coverage

National Meeting Presentation | Evolving Approaches for Vaccination Coverage Assessment of Young Children

National Meeting Presentation | Advances in EHR/IIS Interoperability: A 2019 Update

National Meeting Presentation | Connecting Overseas Refugee Vaccination to State Immunization Registries

National Meeting Presentation | IIS Data Quality Evaluation in Two Remote Island Jurisdictions

National Meeting Presentation | Something Old and Something New: Understanding HL7 Immunization Standards

National Meeting Presentation | Using IIS Data to Estimate National Vaccination Coverage

National Meeting Presentation | Updates on Branch Strategies for Success in an Interconnected Era

National Meeting Presentation | Future of IIS: Sustainability Strategies

National Meeting Presentation | IIS Data Use in Low-Resource Settings: Assessment, Outbreak Response, and Evaluation

National Meeting Presentation | Value of IIS Data for Monitoring Vaccination at the National Level

National Meeting Presentation | Recent Developments with the National Immunization Survey-Child

National Meeting Presentation | A Dashboard for Tracking Progress Toward Achieving the IIS Functional Standards

National Meeting Presentation | Use of IIS for Program Interventions – Chuuk, Federated States of Micronesia

National Meeting Presentation | Serogroup B Meningococcal Vaccine: A First Look at Uptake and Coverage

National Meeting Presentation | Health Level 7 Implementation Guide: Current and Future States

National Meeting Presentation | Advances in EHR/IIS Interoperability by Select Immunization Programs

National Meeting Presentation | Creating a Path Forward for IIS Sustainability

National Meeting Presentation | Strategies to Improve Provider Access to US Refugee Vaccination Records

National Meeting Presentation | Scaling 2D Vaccine Barcode Scanning

Six IIS sites, all funding recipients from the CDC Sentinel Site Project, participated in collaborative analyses to identify and measure the effect of Denominator Inflation in their IIS.

CDC has released its 2018-2020 CDC Immunization Information Systems Strategic Plan. The new plan supports the advancement of IISs by focusing on four strategic priorities: enhancing IIS performance, sustaining the IIS community, influencing and monitoring the ...

This document sets forth the IIS Functional Standards and Operational Guidance Statement (OGS) to guide the direction and progress of IISs over the next five years.

This database contains IIS guidance documents, references for IIS-related articles published in peer-reviewed journals, and Morbidity and Mortality Weekly Reports (MMWRs) from 1999 to the present. Links are provided for documents produced by the CDC. This data...

Use of IIS for Determining Compliance with School Vaccination Requirements

National Meeting Presentation | CDSi Version 3.0: Updates and Enhancements

National Meeting Presentation | Estimating U.S. National Vaccination Coverage Using IIS Sentinel Site Data

National Meeting Presentation | Understanding the NIS and Its Relationship with IIS

National Meeting Presentation | Coming Attraction: Vaccine Code Sets Management Service Center

National Meeting Presentation | Update on Adult Vaccinations and Immunization Information Systems, 2015

National Meeting Presentation | The AFIX-IIS Integration Project—The Good, the Bad and Lessons Learned

National Meeting Presentation | All We Need to Know We Learned in Kindergarten

National Meeting Presentation | Everybody In? Let's Update the IIS Functional Standards Together

Report | The General Best Practice Guidelines for Immunization is available. These guidelines for immunization go beyond vaccination recommendations to give providers guidelines on vaccination practice

National Meeting Presentation | Public Health Impact of VTrckS ExIS Implementation

Tdap and influenza vaccination coverage was assessed among pregnant women in Minnesota. Overall, coverage with Tdap vaccine was 58.2% and with influenza vaccine was 45.9%. Coverage varied based on prenatal care and mother’s race, country of birth or region, ...

National Meeting Presentation | Frequency of Vaccinations Outside Recommended Ages — 2014; Six IIS Sentinel Sites

National Meeting Presentation | Trends in Compliance with Two-dose Influenza Vaccine Recommendations in Young Children, 2010–2015

National Meeting Presentation | A Tale of Two Collaborators: The IIS Sentinel Site Project and CDC

National Meeting Presentation | Progress Update on Automating VTrckS ExIS Data Exchange and the ExIS Usability Best Practices Catalog

National Meeting Presentation | An Update on Two-Dimensional (2D) Vaccine Barcoding

National Meeting Presentation | Knowledge and Use of IIS Among a National Network of Physician Primary-care Providers

National Meeting Presentation | New and Existing Acquisition Mechanisms to Support IIS Strategic Initiatives

National Meeting Presentation | Plenary: Partnering With IIS for the Future

National Meeting Presentation | Two-Dimensional (2D) Vaccine Barcoding

National Meeting Presentation | Clinical Decision Support for Immunization: Using the Resources Effectively

National Meeting Presentation | VTrckS ExIS: Three Projects that Build on Current Successes

National Meeting Presentation | IIS Sentinel Site Contributions to Pandemic Preparedness and Response Planning

National Meeting Presentation | VTrckS ExIS: Successes and Future Direction

National Meeting Presentation | What's Going On: An Update on Clinical Decision Support for Immunization