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From Complexity to Clarity: The Role of CDS in Immunizations One-Sheet

This one-sheet provides a high-level overview of the role of Clinical Decision Support (CDS) in immunizations. It highlights key functions, benefits, and emerging considerations for maintaining clear and consistent vaccine guidance as schedules and policies ev...

From EHR Immunization Requirements to a Validation and Recognition Program

From EHR Immunization Requirements to a Validation and Recognition Program

Issued on April 20, 2017 by CNI Advantage, HIMSS, ICSA Labs

National Meeting Presentation | From EHR Immunization Requirements to a Validation and Recognition Program

From Manager to Team: Diversifying Your IIS Leadership to Meet Demands

From Manager to Team: Diversifying Your IIS Leadership to Meet Demands

Issued on April 29, 2025 by Minnesota Department of Health

National Meeting Presentation | From Manager to Team: Diversifying Your IIS Leadership to Meet Demands (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete without the a...

From Muddled to Methodized: Onboarding in Minnesota

National Meeting Presentation | From Muddled to Methodized: Onboarding in Minnesota

From Presentation to Publication: Advice from the AIRA Publication Workgroup

From Presentation to Publication: Advice from the AIRA Publication Workgroup

Issued on May 2, 2023 by Oregon Immunization Program, HLN Consulting LLC, Minnesota Department of Health, University of Michigan

National Meeting Presentation | From Presentation to Publication: Advice from the AIRA Publication Workgroup (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2023 National Meeting and are incomplete without...

From Rejection to Resolution: Optimizing Virginia’s HL7 VXU Message Workflow

From Rejection to Resolution: Optimizing Virginia’s HL7 VXU Message Workflow

Issued on April 29, 2025 by Virginia Department of Health

National Meeting Presentation | From Rejection to Resolution: Optimizing Virginia’s HL7 VXU Message Workflow (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2025 National Meeting and are incomplete witho...

From Requirements to Go-Live: The Epic Journey of an IIS Platform Transition

National Meeting Presentation | From Requirements to Go-Live: The Epic Journey of an IIS Platform Transition

From the Simple to the Complex: IIS Provider Training in MN and LA

From the Simple to the Complex: IIS Provider Training in MN and LA

Issued on May 3, 2024 by Minnesota Department of Health, Louisiana Department of Health and Hospitals

National Meeting Presentation | From the Simple to the Complex: IIS Provider Training in MN and LA (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accom...

Functional Standards Update

Functional Standards Update

Issued on September 19, 2012 by CDC

National Meeting Presentation | Functional Standards Update

Fundamentals of IIS: HL7 Basics

Fundamentals of IIS: HL7 Basics

Issued on January 24, 2023 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to explain the key concepts of HL7 specific to IIS. Learners will explore what HL7 is, why it is used for immunization messaging, how it works, what the impacts of HL7 messaging are on IIS, and...

Fundamentals of IIS: Interoperability

Fundamentals of IIS: Interoperability

Issued on August 18, 2021 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to introduce learners to key concepts related to interoperability and the responsibilities of the IIS. This course includes information about electronic health records, health information excha...

Funding Options to Fulfill Requests for Data

Funding Options to Fulfill Requests for Data

Issued on February 13, 2017 by AIRA

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AIRA sent out an Information Request from the Washington State Department of Health to the membership to gather the collective expertise of the IIS community regarding funding options to fulfill requests for data

Funding to Support IIS Operations

Funding to Support IIS Operations

Issued on September 19, 2019 by AIRA

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AIRA sent out an Information Request from the Nevada Department of Health and Human Services to the membership to gather the collective expertise of the IIS community regarding funding to support IIS operations.

Future of IIS: Sustainability Strategies

Future of IIS: Sustainability Strategies

Issued on September 20, 2018 by CDC

National Meeting Presentation | Future of IIS: Sustainability Strategies

Gamification Strategies Applied to IIS Training Within a Learning Management System

Gamification Strategies Applied to IIS Training Within a Learning Management System

Issued on May 3, 2024 by STChealth, Mississippi State Department of Health

National Meeting Presentation | Gamification Strategies Applied to IIS Training Within a Learning Management System (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete ...

General Best Practice Guidelines for Immunization

Report | The General Best Practice Guidelines for Immunization is available. These guidelines for immunization go beyond vaccination recommendations to give providers guidelines on vaccination practice

General Query

Issued on March 26, 2024 by Philadelphia Department of Public Health

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Purpose: To get count of patients Outcome: To get count of patients Format: Single field Audience: IIS staff

Geographic Coverage Analysis and Location Optimization for Vaccine Providers

Geographic Coverage Analysis and Location Optimization for Vaccine Providers

Issued on May 3, 2024 by Virginia Department of Health

National Meeting Presentation | Geographic Coverage Analysis and Location Optimization for Vaccine Providers (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without...

Geographic Distribution of HPV Vaccination Coverage Among Adolescents in North Dakota

National Meeting Presentation | Geographic distribution of HPV Vaccination Coverage among Adolescents in North Dakota

Get SMaRT (AFIX)!

Get SMaRT (AFIX)!

Issued on September 1, 2018 by CDC, IN

National Meeting Presentation | Get SMaRT (AFIX)!

Getting Ready for Meaningful Use Stage 3

Getting Ready for Meaningful Use Stage 3

Issued on December 19, 2016 by AIRA

Webinar | AIRA's Education Steering Committee hosted a community-wide presentation on preparing for Meaningful Use Stage 3

Global Perspectives

Global Perspectives

Issued on September 15, 2020 by AIRA, Path, IRD Global, University of Chile

Select AIRA 2020 National Meeting Presentations: Learn about how electronic immunization registries are used all over the globe to track and improve immunization rates worldwide

Going Small in Utah: Identifying Immunization Pockets Of Need: Small Area Analysis of IIS Data To Detect Undervaccinated Populations

National Meeting Presentation | Going Small in Utah: Identifying Immunization Pockets Of Need: Small Area Analysis of IIS Data To Detect Undervaccinated Populations

Going Small: Strategies for Identifying Local Pockets of Need

Going Small: Strategies for Identifying Local Pockets of Need

Issued on April 25, 2017 by CDC, MN, OR, MI, NYC

National Meeting Presentation | Going Small: Strategies for Identifying Local Pockets of Need

Growth from COVID-19; Lessons and Strategies to Inform our IIS Future

Growth from COVID-19; Lessons and Strategies to Inform our IIS Future

Issued on April 27, 2022 by Envision Technology Partners, Inc.

National Meeting Presentation | Growth from COVID-19; Lessons and Strategies to Inform our IIS Future (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2022 National Meeting and are incomplete without the ac...

Guardians of Immunization Adherence: Cosmic Reminder/Recall

Guardians of Immunization Adherence: Cosmic Reminder/Recall

Issued on May 3, 2024 by Docket Health, Inc., Alaska Department of Health

National Meeting Presentation | Guardians of Immunization Adherence: Cosmic Reminder/Recall (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accompanying...

Guidance for HL7 Acknowledgement Messages to Support Interoperability

Clarification on implementation methods in an effort to point all IIS towards common, standardized ACK messaging

Guidance for HL7 RSP Messages to Support Interoperability

This guidance document seeks to clarify how to populate the Acknowledgment Code (MSA-1), the Query Response Status (QAK-2) and the Error Severity (ERR-4) to ensure that all values are in agreement and are appropriate for the outcomes of the processing of the i...

Guidance on Detailed Message Structure and the Use of Specific LOINC Codes

This document contains best practice recommendations from AIRA’s SISC and the CDC on how to structure and populate VXU and RSP messages using specific LOINC codes to include observations such as patient immunity, refusals, indications/contraindications and a...

Guidance on Indicating Clinical Trial Vaccines

Vaccination events that occur as part of clinical trial can be reported to IIS under pre-defined circumstances. This guidance document provides an HL7 method to indicate the vaccination event was part of a clinical trial. It also provides additional considerat...

Guidance on Indicating Preferable and Contraindicated Vaccines

This document outlines an approach to specify preferred or contraindicated vaccine types in a response message

Guidance on Messaging Preferred Name of Patient

Gender-marginalized individuals face significant barriers to adequate and culturally responsive health care, leading to numerous health disparities. The preferred name is the name that should be used when addressing or referencing the patient. For the purposes...

Guidance on Populating OBX-14

Guidance on Populating OBX-14

Issued on September 6, 2019 by AIRA

This document provides guidance on how to populate OBX-14 for common observation types

Guidance on Unit of Sale/Unit of Use Lot Numbers

Guidance on Unit of Sale/Unit of Use Lot Numbers

Issued on June 14, 2018 by AIRA, CDC

This guidance clarifies the process and sets expectations for management of varied vaccine lot numbers, and shares the results of a survey of vaccine manufacturers regarding their practices in assigning Unit of Sale and Unit of Use lot numbers using a pattern,...

Handling IIS Opt-Outs

Handling IIS Opt-Outs

Issued on July 22, 2021 by AIRA

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AIRA sent out an Information Request to the membership to gather the collective expertise of the IIS community regarding handling IIS Opt-Outs

Hands-On with IIS Training Solutions & Workforce Development

Hands-On with IIS Training Solutions & Workforce Development

Issued on April 24, 2017 by CDC, PHII, Intellix Solutions LLC

National Meeting Presentation | Hands-On with IIS Training Solutions & Workforce Development

Harnessing Electronic Clinical Data to Report Adult and Prenatal Immunization Quality Measures

Harnessing Electronic Clinical Data to Report Adult and Prenatal Immunization Quality Measures

Issued on July 19, 2021 by Journal of the American Medical Informatics Association

Journal of the American Medical Informatics Association article exploring the use of health plan quality measures specified for electronic clinical data to monitor immunizations

Having the Right Staff to Support and Maintain Quality Data

Having the Right Staff to Support and Maintain Quality Data

Issued on April 26, 2022 by CDC/NCIRD/ISD/IISSB, Public Health Informatics Institute

National Meeting Presentation | Having the Right Staff to Support and Maintain Quality Data (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2022 National Meeting and are incomplete without the accompanying...

Health Dashboards for Oklahoma: Tools to Strategize Vaccination Mobility and Improvements

Health Dashboards for Oklahoma: Tools to Strategize Vaccination Mobility and Improvements

Issued on May 3, 2024 by Oklahoma State Department of Health

National Meeting Presentation | Health Dashboards for Oklahoma: Tools to Strategize Vaccination Mobility and Improvements (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incom...

Health Data, Technology, and Interoperability: Patient Engagement, Information Sharing, and Public Health Interoperability (HTI-2) Proposed Rule - AIRA IIS Community Comments on HTI-2

On October 4, 2024, AIRA submitted IIS community comments on ONC's latest NPRM. These comments were collected and consolidated from across the community and reviewed by AIRA's Standards and Interoperability Steering Committee (SISC)

Health Department VFC Wastage

Issued on December 16, 2024 by TN

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Purpose: This report summarizes VFC inventory that has been marked as “wastage” (wasted, spoiled, or expired) within the previous month. Data is summarized by overall wastage by vaccine and by individual provider. Outcome: This script outputs a three-ta...

Health Information Systems' Impact on Data Quality and Use in a Global Context

National Meeting Presentation | Health Information Systems' Impact on Data Quality and Use in a Global Context

Health Insurance Claims-IIS Data Linkage for Post- Vaccination Surveillance

Health Insurance Claims-IIS Data Linkage for Post- Vaccination Surveillance

Issued on May 3, 2023 by US Food and Drug Administration

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National Meeting Presentation | Health Insurance Claims-IIS Data Linkage for Post- Vaccination Surveillance (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2023 National Meeting and are incomplete without ...

Health Level 7 Implementation Guide: Current and Future States

National Meeting Presentation | Health Level 7 Implementation Guide: Current and Future States

Health Level 7 Web Service Search Success Rates in New York City’s Citywide Immunization Registry

National Meeting Presentation | Health Level 7 Web Service Search Success Rates in New York City’s Citywide Immunization Registry

Health Plans Using QBP to Query Members for HEDIS Measures

Health Plans Using QBP to Query Members for HEDIS Measures

Issued on October 2, 2019 by AIRA

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AIRA sent out an Information Request from the Oregon Immunization Program to the membership to gather the collective expertise of the IIS community regarding health plans using QBP to query members for HEDIS measures

HEDIS Process

HEDIS Process

Issued on August 18, 2022 by AIRA

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AIRA sent out an Information Request to the membership to gather the collective expertise of the IIS community regarding Medicaid match funding

HEDIS Reporting Service Charges

HEDIS Reporting Service Charges

Issued on October 24, 2024 by AIRA

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AIRA sent out an Information Request to the membership to gather the collective expertise of the IIS community regarding HEDIS reporting service charges

HEDIS Requests

HEDIS Requests

Issued on July 10, 2018 by AIRA

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AIRA sent out an Information Request from the Mississippi State Department of Health to the membership to gather the collective expertise of the IIS community regarding HEDIS requests

Helping IIS Stakeholders Help Themselves! Driving Daily Business Processes With Self-Serve Resources

National Meeting Presentation | Helping IIS Stakeholders Help Themselves! Driving Daily Business Processes With Self-Serve Resources

Hep A and Hep B Vaccination Coverage Among High-Risk Individuals in Wisconsin

National Meeting Presentation | Hep A and Hep B Vaccination Coverage Among High-Risk Individuals in Wisconsin

HHS Vision for Technology Support of Health IT

HHS Vision for Technology Support of Health IT

Issued on August 13, 2019 by U.S. Department of Health and Human Services

National Meeting Presentation | HHS Vision for Technology Support of Health IT

HL7 Data Quality Tool: Transformation to a General Purpose Open- Source Tool

National Meeting Presentation | HL7 Data Quality Tool: Transformation to a General Purpose Open- Source Tool

HL7 Frequently Asked Questions

HL7 Frequently Asked Questions

Issued on December 8, 2021 by AIRA

HL7 Frequently Asked Questions – Updated December 2021 The HL7 FAQ includes guidance on topics such as patient protection indicators, timestamp format, and messaging immunities. The FAQ has been reformatted for ease of use.

HL7 Timeliness and Completeness in the Michigan Care Improvement Registry (MCIR)

National Meeting Presentation | HL7 Timeliness and Completeness in the Michigan Care Improvement Registry (MCIR)

HL7 v2.5.1 Acknowledgment (ACK) Messages and their Role in Ensuring Immunization Interoperability

Objective This on-demand eLearning is designed to strengthen the IIS community’s knowledge and skills in using ACK messages to facilitate immunization data interoperability across systems, in alignment with the National IG. Learning Objectives Upon...

HL7 v2.5.1 Immunization Update (VXU) Messages Course

Objective This on-demand eLearning is designed to enhance the knowledge and skills of the IIS community in using VXU messages to support the interoperability of immunization information between systems in alignment with the National IG. Learning Object...

Dated Immunization IG, no longer in use. Use only for reference

Dated Immunization IG, no longer in use. Use only for reference