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Clinical Decision Support Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Clinical Decision Support (CDS) Validation

Clinical Decision Support Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Clinical Decision Support (CDS) Validation

Data Quality Incoming/Ongoing Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Data Quality Incoming/Ongoing Validation

Data Quality Incoming/Ongoing Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Data Quality Incoming/Ongoing Validation

Query and Response Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Query and Response Validation

Query and Response Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Query and Response Validation

Submission and Acknowledgment Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Submission and Acknowledgment Validation

Transport Validation: Basic Level

Transport Validation: Basic Level

Issued on October 20, 2025 by AIRA

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Transport Validation

Transport Validation: Complete Level

Transport Validation: Complete Level

Issued on October 20, 2025 by AIRA

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Transport Validation

Envision's Webinar: Modernization and Beyond - Envision's Plan for the Future of Public Health Technology

Envision's Webinar: Modernization and Beyond - Envision's Plan for the Future of Public Health Technology

Issued on September 10, 2025 by AIRA

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This webinar focused on broad modernization efforts Envision has planned for their immunization platform, WebIZ™, as well as how Envision is approaching public health technology modernization as a whole including disease and syndromic surveillance, AI, host...

Discovery Session: Unlocking the Future: Emerging Standards in Focus

This Discovery Session took a deeper look at AIRA’s Emerging Standards initiative and how we’re approaching modernization, including our framework for adopting FHIR for specific projects shaping the future of immunization interoperability. The session s...

IIS Product Testing and Validation

IIS Product Testing and Validation

Issued on July 15, 2025 by AIRA

IIS Product Testing and Validation is an annual process that provides IIS technology partners with objective, independent testing of their platform as they make improvements to achieve alignment with community-selected measures and tests. Product testing will ...

Measures and Testing for IIS Validation - Query and Response

Final IIS Validation measures and tests related to query and response developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Measures and Tests for IIS Validation - Submission and Acknowledgment

Final IIS Validation measures and tests related to submission and acknowledgment developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Measures and Tests for IIS Validation - Transport

Final IIS Validation measures and tests related to transport developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Health Data, Technology, and Interoperability: Patient Engagement, Information Sharing, and Public Health Interoperability (HTI-2) Proposed Rule - AIRA IIS Community Comments on HTI-2

On October 4, 2024, AIRA submitted IIS community comments on ONC's latest NPRM. These comments were collected and consolidated from across the community and reviewed by AIRA's Standards and Interoperability Steering Committee (SISC)

Acronyms Within the IIS Community

Issued on July 1, 2024 by AIRA

A list of common acronyms within the IIS community

HL7 v2.5.1 Immunization Update (VXU) Messages Course

Objective This on-demand eLearning is designed to enhance the knowledge and skills of the IIS community in using VXU messages to support the interoperability of immunization information between systems in alignment with the National IG. Learning Object...

Characterizing Clinical Decision Support for HPV Vaccination in Immunization Information Systems

National Meeting Presentation | Characterizing Clinical Decision Support for HPV Vaccination in Immunization Information Systems (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and ar...

Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness

Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness

Issued on May 3, 2024 by Louisiana Department of Health and Hospitals, STChealth

National Meeting Presentation | Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and...

Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability

Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability

Issued on May 3, 2024 by AIRA, CDC/NCIRD/ISD/IDAB

National Meeting Presentation | Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the...

IIS Interoperability Roundup

IIS Interoperability Roundup

Issued on May 3, 2024 by HLN Consulting

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National Meeting Presentation | IIS Interoperability Roundup (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accompanying oral commentary and discussion...

Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics

Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics

Issued on May 3, 2024 by California Department of Public Health, Accenture

National Meeting Presentation | Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete wit...

Sneak Peek at the Next National Implementation Guide Release

Sneak Peek at the Next National Implementation Guide Release

Issued on May 3, 2024 by CDC/NCIRD/ISD/IDAB

National Meeting Presentation | Sneak Peek at the Next National Implementation Guide Release (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accompanyin...

Standardizing and Digitizing Local Implementation Guides for Seamless Data Sharing

National Meeting Presentation | Standardizing and Digitizing Local Implementation Guides for Seamless Data Sharing (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete w...

AIRA Discovery Session: Updates to the IIS Functional Standards

During this session, you'll hear about Updates to the IIS Functional Standards. Presentation includes: • IIS Functional Standards Update Project from Candace Garcia, PHII; Marcey Propp, PHII; Brittany Ersery-Kemp, HLN

Interoperability Between Post-Acute and Long-Term Care (PALTC) and IIS

Despite the adoption of health information technology among healthcare providers and public health support for standards-based immunization data exchange, there is a lack of interoperability between Post-Acute and Long-Term Care (PALTC) EHRs and IIS. These res...

Data Entry Error Guide Template

Data Entry Error Guide Template

Issued on September 7, 2023 by Immunization Integration Program

This template is intended for use by immunization information systems (IIS) to develop a short list of errors, and ways to avoid them, that may occur when users enter data into their organization’s electronic health record/health information technology (EHR/...

Top Five Strategies for Improving Immunization Data Quality at the Point of Care

Top Five Strategies for Improving Immunization Data Quality at the Point of Care

Issued on September 7, 2023 by Immunization Integration Program

This user-friendly infographic highlights five key strategies and related resources to support improving your immunization data quality and reducing rejections

Training Resources for Vaccine Data Entry Users

Training Resources for Vaccine Data Entry Users

Issued on September 7, 2023 by Immunization Integration Program

This guide lists training resources that promote best practices for data validation in the EHR prior to submission to the IIS

IIS Orientation to Provider Onboarding: Resources Checklist

The IIS Orientation to Provider Onboarding: Resources Checklist serves as a starting point for staff who are new to an IIS onboarding role and/or are new to interoperability as it relates to immunization messaging

Assessing the Immunization Information System and Electronic Health Record Interface Accuracy for COVID-19 Vaccinations

Immunizations in the United States are given in many different settings including pharmacies, doctors’ offices, and health departments. After a vaccine is administered, the information is uploaded to an Immunization Information System (IIS), usually run by t...

AIRA Consolidated Comments on ONC's Health Data, Technology, and Interoperability: Certification Program Updates, Algorithm Transparency, and Information Sharing (HTI-1) Notice of Proposed Rule Making (NPRM)

On June 20, 2023, AIRA submitted IIS community comments on ONC's latest NPRM. These comments were collected and consolidated from across the community and reviewed by AIRA's Standards and Interoperability Steering Committee (SISC)

Fundamentals of IIS: HL7 Basics

Fundamentals of IIS: HL7 Basics

Issued on January 24, 2023 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to explain the key concepts of HL7 specific to IIS. Learners will explore what HL7 is, why it is used for immunization messaging, how it works, what the impacts of HL7 messaging are on IIS, and...

Monkeypox Preferred Select Codes

Monkeypox Preferred Select Codes

Issued on November 3, 2022 by AIRA

This document addresses select codes for monkeypox that are not clearly articulated in interoperability documents. These codes were approved by AIRA’s Standards and Interoperability Steering Committee (SISC, a diverse committee with broad representation from...

How Vaccine Status Information Is Accessed and Shared

How Vaccine Status Information Is Accessed and Shared

Issued on January 21, 2022 by Future of Personal Health

Future of Personal Health article regarding the access and sharing of vaccination records

Foundational Guidance for Minimum Functionality to Improve Visibility and Access to Information from Acknowledgment Messages

Describes the process of summarizing acknowledgement messages (ACKs) in aggregate reports produced by IIS, EHRs and third-parties. ACKs are most helpful when they are summarized, reviewed and acted upon. The information contained within acknowledgment reports ...

Connecting Systems

Issued on November 30, 2021 by AIRA

Objective The objective of the Connecting Systems course is to provide a fundamental understanding of digital information encoding for both transmission and storage. Learning Outcomes Digital Data Representation: Understand that all digital data is...

AIRA Discovery Session: Interoperability Course

This session is an introduction to AIRA’s Interoperability Course. This course was designed in response to community needs to support staff working on IIS interoperability topics. In this Discovery Session you will learn about the course format, hear from pa...

Fundamentals of IIS: Interoperability

Fundamentals of IIS: Interoperability

Issued on August 18, 2021 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to introduce learners to key concepts related to interoperability and the responsibilities of the IIS. This course includes information about electronic health records, health information excha...

AIRA Town Hall: Basic and Complete Validation for Data Quality Incoming/Ongoing (DQI)

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to introduce the proposed Basic and Complete Validation for Data Quality Incoming/Ongoing (DQI)

AIRA Discovery Session: An Orientation to AIRA for New IIS Staff

A Discovery Session webinar focused on topic areas relevant for all IIS Managers but specifically target new(er) IIS Managers, staff, and those new to the IIS community

Immunization Information System (IIS) Information Session

AIRA webinar designed to help increase your knowledge about immunization information systems (IIS), also known as immunization registries. This session will cover IIS functionality and standards, policies, the impact of COVID-19 on IIS, and how data in IIS ma...

AIRA Letter and Comments on ONC's USCDI V2

AIRA Letter and Comments on ONC's United States Core Data for Interoperability, Version 2

AIRA Adult IIS Literature Review

AIRA Adult IIS Literature Review

Issued on February 26, 2021 by AIRA

An Environmental Scan on Progress, Challenges, and Opportunities: Expanding Immunization Information Systems for Adults in the United States

Preparing for COVID-19 Vaccination: A Call to Action for Clinicians on Immunization Information Systems

Annals of Internal Medicine article regarding a call to action for clinicians on IIS in preparation for COVID-19 vaccination

COVID-19 Vaccination Response Planning

COVID-19 Vaccination Response Planning

Issued on October 27, 2020 by AIRA

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Webinar covering current response planning information and presentations from jurisdictions

Measurement & Improvement - AIRA 2020 National Meeting Presentations

Select AIRA 2020 National Meeting Presentations: Learn about IIS community success, data at rest pilots, and Measurement and Improvement (M&I) 2020 Validation recognition If you are interested in listening to a recording of this webinar, please email info@imm...

IIS Operations Tools

IIS Operations Tools

Issued on September 22, 2020 by PHII

The IIS Operations Tools page empowers IIS staff to navigate the various processes involved in managing and maintaining the day-to-day operations of a well functioning IIS. This set of tools was developed by the Public Health Informatics Institute with input f...

IIS Operations

IIS Operations

Issued on September 8, 2020 by AIRA, MN, HLN, CDC, PHII

Select AIRA 2020 National Meeting Presentations: Learn about IIS operations and security

AART User Group Mini-Series

AART User Group Mini-Series

Issued on July 22, 2020 by AIRA

Mini-series to promote and support the use of AART as a means for IIS to more quickly and efficiently align with national standards and priorities.

AIRA Town Hall: Proposed Submission & Acknowledgment Validation Update

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to discuss Acknowledgment (ACK) Processing Rules and Proposed 2021 Submission & Acknowledgment Validation including NDC Measures 15 an...

AIRA Town Hall: Proposed Measures for Incoming/Ongoing Data, CDS Assessment Thresholds, and CDS Validation

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to introduce the proposed measures for Incoming/Ongoing Data, CDS Assessment Thresholds, and CDS Validation

IIS Measurement and Improvement Summary

IIS Measurement and Improvement Summary

Issued on December 31, 2019 by AIRA

Summary of the IIS Measurement and Improvement process developed by the Measurement for Assessment and Certification Workgroup (MACAW)

IIS Measurement and Improvement: Testing and Discovery, Assessment and Validation Overview

Overview of the three stages of the IIS Measurement and Improvement process developed by the Measurement for Assessment and Certification Workgroup (MACAW)

Business Continuity Planning for Immunization Information System Programs

The purpose of this guide is to help IIS programs develop and implement business continuity plans and management systems.

Tricks (and Treats) for Promoting an IIS

Webinar hosted by AIRA's Education Steering Committee providing information about the one-sheet resources, a quick explanation of how to add your logo, and ideas for promoting your IIS