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Clinical Decision Support Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Clinical Decision Support (CDS) Validation

Clinical Decision Support Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Clinical Decision Support (CDS) Validation

Data Quality Incoming/Ongoing Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Data Quality Incoming/Ongoing Validation

Data Quality Incoming/Ongoing Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Data Quality Incoming/Ongoing Validation

Query and Response Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Query and Response Validation

Query and Response Validation: Complete Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Query and Response Validation

Submission and Acknowledgment Validation: Basic Level

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Submission and Acknowledgment Validation

Discovery Session: Data at Rest, Quality in Motion — Real-World Stories from Jurisdictions

During this Discovery Session, Arizona and Texas shared how they’ve leveraged the Data at Rest (DAR) Measurement & Improvement content area to enhance IIS data quality. Arizona showcased reporting and visualization tools that improve completeness, validity, ...

Transport Validation: Basic Level

Transport Validation: Basic Level

Issued on October 20, 2025 by AIRA

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the basic level of Transport Validation

Transport Validation: Complete Level

Transport Validation: Complete Level

Issued on October 20, 2025 by AIRA

This report shares results of IIS who participated in Validation as the third stage of the voluntary, phased Measurement and Improvement process. This report provides results for the complete level of Transport Validation

Discovery Session: From Extract to Impact – Lessons Learned from the Patient Matching, Extract Pilot

This session highlighted the role of accurate patient matching in IIS data quality and shared key takeaways from AIRA’s second pilot, including enhancements to the tool, lessons learned, and how the findings can inform IIS programs moving forward. Whether...

Envision's Webinar: Modernization and Beyond - Envision's Plan for the Future of Public Health Technology

Envision's Webinar: Modernization and Beyond - Envision's Plan for the Future of Public Health Technology

Issued on September 10, 2025 by AIRA

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This webinar focused on broad modernization efforts Envision has planned for their immunization platform, WebIZ™, as well as how Envision is approaching public health technology modernization as a whole including disease and syndromic surveillance, AI, host...

Discovery Session: Unlocking the Future: Emerging Standards in Focus

This Discovery Session took a deeper look at AIRA’s Emerging Standards initiative and how we’re approaching modernization, including our framework for adopting FHIR for specific projects shaping the future of immunization interoperability. The session s...

IIS Product Testing and Validation

IIS Product Testing and Validation

Issued on July 15, 2025 by AIRA

IIS Product Testing and Validation is an annual process that provides IIS technology partners with objective, independent testing of their platform as they make improvements to achieve alignment with community-selected measures and tests. Product testing will ...

Measures and Testing for IIS Validation - Query and Response

Final IIS Validation measures and tests related to query and response developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Measures and Tests for IIS Validation - Submission and Acknowledgment

Final IIS Validation measures and tests related to submission and acknowledgment developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

Measures and Tests for IIS Validation - Transport

Final IIS Validation measures and tests related to transport developed by the Measurement for Assessment and Certification Workgroup (MACAW) as part of the IIS measurement and improvement process

AIRA Discovery Session: AIRA 2025 National Meeting Highlights

This session showcased key highlights from the AIRA 2025 National Meeting including recaps of the following highly rated breakout sessions: • Closing the Gap: A Data-Driven Approach to Address Health Gaps in NC from Jenny Myers, MPH, North Carolina Departme...

M&I Discovery Session: Patient Matching | A Town Hall

During this Discovery Session, presenters discussed the next steps for Patient Matching – HL7 as part of AIRA’s Measurement and Improvement (M&I) Initiative. The draft Measures and Tests for Patient Matching – HL7 document was reviewed with the IIS commu...

AIRA Discovery Session: Insights from 20 Million Immunization Data Exchanges Between VA and IIS

During the session, presenters discussed immunization data exchange after 20 million immunization messages were exchanged. The US Department of Veterans Affairs (VA) has been exchanging, tracking, and analyzing immunization messages to understand the reasons b...

Health Data, Technology, and Interoperability: Patient Engagement, Information Sharing, and Public Health Interoperability (HTI-2) Proposed Rule - AIRA IIS Community Comments on HTI-2

On October 4, 2024, AIRA submitted IIS community comments on ONC's latest NPRM. These comments were collected and consolidated from across the community and reviewed by AIRA's Standards and Interoperability Steering Committee (SISC)

AIRA Discovery Session: Advancing IIS Interoperability: The Local IG Digitization and Standardization Project Unveiled

During the session, presenters discussed the Digitization and Standardization project and shared how digitized local IGs in IGAMT (NIST’s Implementation Guide Authoring and Management Tool) can be used to create a cost-free, jurisdiction-specific test tool. ...

AIRA Discovery Session: Moving Needles: Increasing Connectivity Between Post-Acute and Long-Term Care (PALTC) EHRs and IIS

During this session, presenters from the Society for Post-Acute and Long-term Care Medicine Inc. (AMDA) and AIRA discuss Moving Needles, a CDC-funded initiative to increase the connectivity between Post-Acute and Long-Term Care (PALTC) EHRs and IIS

Acronyms Within the IIS Community

Issued on July 1, 2024 by AIRA

A list of common acronyms within the IIS community

HL7 v2.5.1 Immunization Update (VXU) Messages Course

Objective This on-demand eLearning is designed to enhance the knowledge and skills of the IIS community in using VXU messages to support the interoperability of immunization information between systems in alignment with the National IG. Learning Object...

AIRA Discovery Session: Emerging Standards

During this session, presenters navigate emerging standards as they support public health data modernization initiatives and provide structured data specifications to meet the needs of public health programs and their partners

Characterizing Clinical Decision Support for HPV Vaccination in Immunization Information Systems

National Meeting Presentation | Characterizing Clinical Decision Support for HPV Vaccination in Immunization Information Systems (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and ar...

Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness

Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness

Issued on May 3, 2024 by Louisiana Department of Health and Hospitals, STChealth

National Meeting Presentation | Effectively Onboarding Providers Through Data Quality Analysis, Ensuring Interoperability Readiness (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and...

Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability

Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability

Issued on May 3, 2024 by AIRA, CDC/NCIRD/ISD/IDAB

National Meeting Presentation | Evolving the IIP EHR Testing Program to Improve EHR IIS Interoperability (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the...

IIS Interoperability Roundup

IIS Interoperability Roundup

Issued on May 3, 2024 by HLN Consulting

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National Meeting Presentation | IIS Interoperability Roundup (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accompanying oral commentary and discussion...

Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics

Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics

Issued on May 3, 2024 by California Department of Public Health, Accenture

National Meeting Presentation | Making ICE Hot! Generating Vaccination Recommendations for Large-Scale Analytics (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete wit...

Sneak Peek at the Next National Implementation Guide Release

Sneak Peek at the Next National Implementation Guide Release

Issued on May 3, 2024 by CDC/NCIRD/ISD/IDAB

National Meeting Presentation | Sneak Peek at the Next National Implementation Guide Release (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete without the accompanyin...

Standardizing and Digitizing Local Implementation Guides for Seamless Data Sharing

National Meeting Presentation | Standardizing and Digitizing Local Implementation Guides for Seamless Data Sharing (Please note: The presentation slides shared provided an outline of presentations given at the AIRA 2024 National Meeting and are incomplete w...

AIRA Discovery Session: Updates to the IIS Functional Standards

During this session, you'll hear about Updates to the IIS Functional Standards. Presentation includes: • IIS Functional Standards Update Project from Candace Garcia, PHII; Marcey Propp, PHII; Brittany Ersery-Kemp, HLN

Interoperability Between Post-Acute and Long-Term Care (PALTC) and IIS

Despite the adoption of health information technology among healthcare providers and public health support for standards-based immunization data exchange, there is a lack of interoperability between Post-Acute and Long-Term Care (PALTC) EHRs and IIS. These res...

Data Entry Error Guide Template

Data Entry Error Guide Template

Issued on September 7, 2023 by Immunization Integration Program

This template is intended for use by immunization information systems (IIS) to develop a short list of errors, and ways to avoid them, that may occur when users enter data into their organization’s electronic health record/health information technology (EHR/...

Top Five Strategies for Improving Immunization Data Quality at the Point of Care

Top Five Strategies for Improving Immunization Data Quality at the Point of Care

Issued on September 7, 2023 by Immunization Integration Program

This user-friendly infographic highlights five key strategies and related resources to support improving your immunization data quality and reducing rejections

Training Resources for Vaccine Data Entry Users

Training Resources for Vaccine Data Entry Users

Issued on September 7, 2023 by Immunization Integration Program

This guide lists training resources that promote best practices for data validation in the EHR prior to submission to the IIS

IIS Orientation to Provider Onboarding: Resources Checklist

The IIS Orientation to Provider Onboarding: Resources Checklist serves as a starting point for staff who are new to an IIS onboarding role and/or are new to interoperability as it relates to immunization messaging

Assessing the Immunization Information System and Electronic Health Record Interface Accuracy for COVID-19 Vaccinations

Immunizations in the United States are given in many different settings including pharmacies, doctors’ offices, and health departments. After a vaccine is administered, the information is uploaded to an Immunization Information System (IIS), usually run by t...

AIRA Consolidated Comments on ONC's Health Data, Technology, and Interoperability: Certification Program Updates, Algorithm Transparency, and Information Sharing (HTI-1) Notice of Proposed Rule Making (NPRM)

On June 20, 2023, AIRA submitted IIS community comments on ONC's latest NPRM. These comments were collected and consolidated from across the community and reviewed by AIRA's Standards and Interoperability Steering Committee (SISC)

Fundamentals of IIS: HL7 Basics

Fundamentals of IIS: HL7 Basics

Issued on January 24, 2023 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to explain the key concepts of HL7 specific to IIS. Learners will explore what HL7 is, why it is used for immunization messaging, how it works, what the impacts of HL7 messaging are on IIS, and...

Monkeypox Preferred Select Codes

Monkeypox Preferred Select Codes

Issued on November 3, 2022 by AIRA

This document addresses select codes for monkeypox that are not clearly articulated in interoperability documents. These codes were approved by AIRA’s Standards and Interoperability Steering Committee (SISC, a diverse committee with broad representation from...

How Vaccine Status Information Is Accessed and Shared

How Vaccine Status Information Is Accessed and Shared

Issued on January 21, 2022 by Future of Personal Health

Future of Personal Health article regarding the access and sharing of vaccination records

Foundational Guidance for Minimum Functionality to Improve Visibility and Access to Information from Acknowledgment Messages

Describes the process of summarizing acknowledgement messages (ACKs) in aggregate reports produced by IIS, EHRs and third-parties. ACKs are most helpful when they are summarized, reviewed and acted upon. The information contained within acknowledgment reports ...

Connecting Systems

Issued on November 30, 2021 by AIRA

Objective The objective of the Connecting Systems course is to provide a fundamental understanding of digital information encoding for both transmission and storage. Learning Outcomes Digital Data Representation: Understand that all digital data is...

AIRA Discovery Session: Interoperability Course

This session is an introduction to AIRA’s Interoperability Course. This course was designed in response to community needs to support staff working on IIS interoperability topics. In this Discovery Session you will learn about the course format, hear from pa...

Fundamentals of IIS: Interoperability

Fundamentals of IIS: Interoperability

Issued on August 18, 2021 by PHII

Part of the Fundamentals of IIS series, the goal of this course is to introduce learners to key concepts related to interoperability and the responsibilities of the IIS. This course includes information about electronic health records, health information excha...

AIRA Town Hall: Basic and Complete Validation for Data Quality Incoming/Ongoing (DQI)

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to introduce the proposed Basic and Complete Validation for Data Quality Incoming/Ongoing (DQI)

AIRA Discovery Session: An Orientation to AIRA for New IIS Staff

A Discovery Session webinar focused on topic areas relevant for all IIS Managers but specifically target new(er) IIS Managers, staff, and those new to the IIS community

Immunization Information System (IIS) Information Session

AIRA webinar designed to help increase your knowledge about immunization information systems (IIS), also known as immunization registries. This session will cover IIS functionality and standards, policies, the impact of COVID-19 on IIS, and how data in IIS ma...

AIRA Letter and Comments on ONC's USCDI V2

AIRA Letter and Comments on ONC's United States Core Data for Interoperability, Version 2

AIRA Adult IIS Literature Review

AIRA Adult IIS Literature Review

Issued on February 26, 2021 by AIRA

An Environmental Scan on Progress, Challenges, and Opportunities: Expanding Immunization Information Systems for Adults in the United States

Preparing for COVID-19 Vaccination: A Call to Action for Clinicians on Immunization Information Systems

Annals of Internal Medicine article regarding a call to action for clinicians on IIS in preparation for COVID-19 vaccination

COVID-19 Vaccination Response Planning

COVID-19 Vaccination Response Planning

Issued on October 27, 2020 by AIRA

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Webinar covering current response planning information and presentations from jurisdictions

Measurement & Improvement - AIRA 2020 National Meeting Presentations

Select AIRA 2020 National Meeting Presentations: Learn about IIS community success, data at rest pilots, and Measurement and Improvement (M&I) 2020 Validation recognition If you are interested in listening to a recording of this webinar, please email info@imm...

IIS Operations Tools

IIS Operations Tools

Issued on September 22, 2020 by PHII

The IIS Operations Tools page empowers IIS staff to navigate the various processes involved in managing and maintaining the day-to-day operations of a well functioning IIS. This set of tools was developed by the Public Health Informatics Institute with input f...

IIS Operations

IIS Operations

Issued on September 8, 2020 by AIRA, MN, HLN, CDC, PHII

Select AIRA 2020 National Meeting Presentations: Learn about IIS operations and security

AART User Group Mini-Series

AART User Group Mini-Series

Issued on July 22, 2020 by AIRA

Mini-series to promote and support the use of AART as a means for IIS to more quickly and efficiently align with national standards and priorities.

AIRA Town Hall: Proposed Submission & Acknowledgment Validation Update

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to discuss Acknowledgment (ACK) Processing Rules and Proposed 2021 Submission & Acknowledgment Validation including NDC Measures 15 an...

AIRA Town Hall: Proposed Measures for Incoming/Ongoing Data, CDS Assessment Thresholds, and CDS Validation

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to introduce the proposed measures for Incoming/Ongoing Data, CDS Assessment Thresholds, and CDS Validation

IIS Measurement and Improvement Summary

IIS Measurement and Improvement Summary

Issued on December 31, 2019 by AIRA

Summary of the IIS Measurement and Improvement process developed by the Measurement for Assessment and Certification Workgroup (MACAW)

IIS Measurement and Improvement: Testing and Discovery, Assessment and Validation Overview

Overview of the three stages of the IIS Measurement and Improvement process developed by the Measurement for Assessment and Certification Workgroup (MACAW)

Business Continuity Planning for Immunization Information System Programs

The purpose of this guide is to help IIS programs develop and implement business continuity plans and management systems.

Tricks (and Treats) for Promoting an IIS

Webinar hosted by AIRA's Education Steering Committee providing information about the one-sheet resources, a quick explanation of how to add your logo, and ideas for promoting your IIS

Letters Confirming Active Engagement for Stage 3 MIPS/Promoting Interoperability

Letters Confirming Active Engagement for Stage 3 MIPS/Promoting Interoperability

Issued on October 2, 2019 by AIRA

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AIRA sent out an Information Request from the Oregon Immunization Program to the membership to gather the collective expertise of the IIS community regarding letters confirming active engagement for Stage 3 MIPS/Promoting Interoperability

Promoting IIS

Promoting IIS

Issued on September 26, 2019 by AIRA

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AIRA sent out an Information Request from AIRA's Education Steering Committee to the membership to gather the collective expertise of the IIS community regarding promoting IIS

AIRA IIS One-Sheets - Add Your Logo

AIRA IIS One-Sheets - Add Your Logo

Issued on September 20, 2019

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Series of one-sheet resources to communicate the role and value of immunization information systems (IIS) for use by the IIS community. Add your logo to this version of the one-sheet resources

Introduction to Clinical Decision Support

Introduction to Clinical Decision Support

Issued on September 3, 2019 by AIRA

A seven-minute video on how to view CDS results in the Aggregate Analysis Reporting Tool (AART) and how view more detailed results through the integrated CDS feature within AART

Query Assessment and How to Improve

Query Assessment and How to Improve

Issued on September 3, 2019 by AIRA

A five-minute video with step-by-step instructions on how to improve your Query results in the Aggregate Analysis Reporting Tool (AART) by using the NIST Immunization Test Suite

AIRA Town Hall: Proposed Additional Submission Measures for Assessment

Webinar | The Measurement for Assessment and Certification Advisory Workgroup (MACAW) held a community wide town hall meeting to introduce the proposed additional Submission measures for Assessment

Measurement & Improvement: From Transport to Decision Support, All Your Questions Answered

National Meeting Presentation | Measurement & Improvement: From Transport to Decision Support, All Your Questions Answered

AIRA Discovery Session: CDS Assessment in AART

This session focused on CDS Assessment in AART and getting the most out of your report

Communication Through Listservs

Communication Through Listservs

Issued on June 12, 2019 by AIRA

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AIRA sent out an Information Request from the Tennessee Department of Health to the membership to gather the collective expertise of the IIS community regarding communication through listservs

AIRA Letter and Comments on ONC's TEFCA Draft 2

AIRA Letter and Comments on ONC's TEFCA Draft 2

AIRA Letter and Comments on the CMS Patient Access and Interoperability Proposed Rules

AIRA Letter and Comments on the CMS Patient Access and Interoperability Proposed Rules

AIRA Letter and Comments on the ONC Interoperability, Information Blocking and Health IT Certification Program Proposed Rules

AIRA Letter and Comments on the ONC proposed rules: 21st Century Cures Act: Interoperability, Information Blocking, and the ONC Health IT Certification Program

AIRA Discovery Session: Considerations When Documenting IIS Service-Level Expectations

This session focused on Service-Level Agreements (SLAs) and provided considerations for documentation of service performance measures across IIS and all services that support IIS.

Measles Outbreak Response

Measles Outbreak Response

Issued on May 28, 2019 by AIRA

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AIRA sent out an Information Request from the Vermont Department of Health to the membership to gather the collective expertise of the IIS community regarding responding to the measles outbreak

AIRA Discovery Session: Functional Guide Volume 2

Overview of the recently released Functional Guide Volume 2: CDC Endorsed Data Elements

CDC Provider IIS Participation Community of Practice

CDC Provider IIS Participation Community of Practice

Issued on April 10, 2019 by AIRA, CDC

Webinar | An overview of the CDC Provider IIS Participation Community of Practice and sharing ideas for addressing important provider IIS participation issues including onboarding, EHR assistance, data quality, and provider training and outreach

AIRA Town Hall: ONC and CMS Proposed Rules

Webinar | AIRA held a community wide town hall meeting to discuss the draft comments on proposed rules from the Office of the National Coordinator for Health Information Technology (ONC), Department of Health and Human Services (HHS) and the Centers for Medica...

Redefining vaccination coverage and timeliness measures using electronic immunization registry data in low- and middle-income countries

This commentary discusses how measures for assessing vaccination status and program performance can be redefined and recalculated using data when generated at the health facility level and the implications of the use and availability of electronic individual-l...

Introduction to Onboarding Consensus-based Recommendations

Webinar | ESC-hosted webinar to introduce the new AIRA guide, Onboarding Consensus-Based Recommendations

AIRA Discovery Session: IIS Dashboard

AIRA Discovery Session: IIS Dashboard

Issued on February 4, 2019 by AIRA, CDC

Demonstration of the new IIS Dashboard

Increasing Provider Participation

Increasing Provider Participation

Issued on January 29, 2019 by AIRA

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AIRA sent out an Information Request from the Tennessee Department of Health to the membership to gather the collective expertise of the IIS community regarding increasing provider participation

AIRA IIS Functional Guide Series

AIRA IIS Functional Guide Series

Issued on January 25, 2019 by AIRA

The IIS Functional Guide series is a new resource within the IIS community that defines the capabilities and requirements an IIS will need in order to enable business functions needed by their end users. The first volume of the IIS Functional Guide focuses on ...

AIRA Letter and Comments on Objectives for Healthy People 2030

AIRA's letter and comments on the Secretary’s Advisory Committee on National Health and Disease Prevention proposed Immunization and Infectious Disease (IID) objectives for Healthy People (HP) 2030

AIRA Discovery Session: CDC’s Provider Onboarding Shared Services for IIS

Information on CDC’s planning for Provider Onboarding Shared Services and opportunity for CDC to hear from attendees about onboarding topics

Designing and implementing an immunisation information system, a handbook for those involved in the design, implementation or management of immunisation information systems

This technical guidance from the European Centre for Disease Prevention and Control collates guiding principles and good practices from all aspects of IIS development and implementation

IIS-EHR Interoperability Common Areas of Variability Based on Jurisdictional Law/Policy

Common areas of variability for IIS-EHR interoperability based on jurisdictional law and policy

Onboarding Consensus-Based Recommendations

Onboarding Consensus-Based Recommendations

Issued on November 15, 2018 by AIRA

The purpose of this AIRA guide is to improve and standardize onboarding. This document is intended for both technical and programmatic staff that make up IIS onboarding teams and program administrators responsible for the allocation of onboarding resources. EH...

AIRA Discovery Session: IIS Interoperability Highlights

In honor of National Health IT Week, some the innovative ways Immunization Information Systems (IIS) support Public Health and Clinical Medicine were presented

ONC 2019 Standards Advisory and AIRA Comments

AIRA Letter and Comments on the ONC 2019 Standards Advisory

MQE Project Tools and Documents

MQE Project Tools and Documents

Issued on September 30, 2018 by AIRA

Tools and documents to support the Message Quality Evaluation (MQE) Tool

Updates from the European Centre for Disease Prevention and Control

National Meeting Presentation | Updates from the European Centre for Disease Prevention and Control